Fig. 1 · Structure
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T0467
Parkin Mitochondrial Translocation Activator
T0467 is a Parkin mitochondrial translocation activator that functions in a PINK1-dependent manner. This compound effectively promotes parkin translocation to mitochondria while not inducing mitochondrial accumulation of PINK1 in dopaminergic neurons. T0467 holds potential for research focusing on the activation of PINK1-Parkin signaling pathways, pertinent to the study of Parkinson’s disease and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 859518-94-8 |
| Applications | Parkin Mitochondrial Translocation Activator |
| Formula | C24H26F3N5 |
| Molecular Weight | 441.49 |
| SMILES | FC1=CC=C(CN2[C@H](CNCC2)C)C=C1C3=NC(NCCC4=CC(F)=CC(F)=C4)=NC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.