T0901317

Catalog No.: A12652

LXR/FXR agonist

T0901317

T0901317 Chemical Structure

CAS NO. 293754-55-9

T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$70.00
50 mg
$100.00
100 mg
$150.00
10mM * 1mL in DMSO
$50.00
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Biological Activity

T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively
Targets
LXR FXR
50 nM(EC50)5 μM(EC50)
In vitro (25°C) DMSO 88 mg/mL (182.82 mM)
Water Insoluble
Ethanol 88 mg/mL (182.82 mM)
In vivo 2% DMSO+35% PEG 300+5% Tween 80+ddH2O 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.78 mL 103.88 mL 207.76 mL
0.5 mM 4.16 mL 20.78 mL 41.55 mL
1 mM 2.08 mL 10.39 mL 20.78 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 481.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12652
Actions Agonist
CAS No. 293754-55-9
Formula C17H12F9NO3S
M. Wt 481.33
Purity >98%
SMILES C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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