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Biological Activity
T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.85 mL | 134.25 mL | 268.5 mL |
| 0.5 mM | 5.37 mL | 26.85 mL | 53.7 mL |
| 1 mM | 2.68 mL | 13.42 mL | 26.85 mL |
| 5 mM | 0.54 mL | 2.68 mL | 5.37 mL |
*The above data is based on the productmolecular weight 372.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16243 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1351926-90-3 |
| Formula | C17H20N6O2S |
| M. Wt | 372.44 |
| Purity | >98% |
| SMILES | CC(C)N1C2=C(C(=N1)CC3=CC(=CC=C3)NS(=O)(=O)C=C)C(=NC=N2)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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