T863

Catalog No.: A11386

DGAT1 inhibitor

T863

T863 Chemical Structure

CAS NO. 701232-20-4

T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells.

Availability: In stock

Package Price Qty
5 mg
$72.00
10 mg
$124.00
50 mg
$368.00
100 mg
$736.00
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Biological Activity

T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells.
In vitro DMSO 73 mg/mL (185.05 mM)
Water Insoluble
Ethanol 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.75 mL 253.5 mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.54 mL 12.68 mL 25.35 mL
5 mM 0.51 mL 2.54 mL 5.07 mL

*The above data is based on the productmolecular weight 394.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11386
Actions Inhibitor
CAS No. 701232-20-4
Formula C22H26N4O3
M. Wt 394.47
Purity >98%
Synonyms T 863, T-863
SMILES O=C(O)C[[email protected]]1CC[[email protected]](C2=CC=C(C3=NC4=C(N)N=CN=C4OC3(C)C)C=C2)CC1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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