Tacaciclib

Catalog No.: A54372
CDK Inhibitor
Tacaciclib is a selective cyclin-dependent kinase (CDK) inhibitor that exerts antineoplastic effects by disrupting cell cycle progression. It primarily targets CDK2 and CDK9, leading to the inhibition of cancer cell proliferation. This compound is useful in cancer research for exploring therapeutic pathways and mechanisms of resistance in tumor models.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTacaciclib is a selective cyclin-dependent kinase (CDK) inhibitor that exerts antineoplastic effects by disrupting cell cycle progression. It primarily targets CDK2 and CDK9, leading to the inhibition of cancer cell proliferation. This compound is useful in cancer research for exploring therapeutic pathways and mechanisms of resistance in tumor models.
Product Information
Catalog NumA54372
FormulaC30H36N6O3
Molecular Weight528.65
CAS Number2768774-66-7
SMILESO=C(NC1=NNC(C2CC2)=C1)[C@H](C3=CC(C4=CN=C(NC(/C=C/CN5CCOCC5)=O)C=C4)=CC=C3)C(C)C
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