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TACE-IN-1

TACE Inhibitor

TACE-IN-1 is a selective inhibitor of tumor necrosis factor-α converting enzyme (TACE) that exhibits oral bioactivity. This compound effectively reduces TNF-α production in human whole blood, making it a valuable tool for studying inflammatory processes. TACE-IN-1 is stable in its neutral form and has applications in anti-inflammatory research, aiding in the exploration of therapeutic interventions for inflammatory diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1219812-22-2
Applications	TACE Inhibitor
Formula	C₂₆H₂₆N₄O₇
Molecular Weight	506.52
SMILES	C([C@@]1(C(=O)N(COC(C(C)(C)C)=O)C(=O)N1)C2=CC=3C(O2)=CC=CN3)N4C(=O)C=5C(C4)=CC=C(OC)C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.