Catalog No.: A10883

PDE5 inhibitor


Tadalafil Chemical Structure

CAS NO. 171596-29-5

Tadalafil is a PDE5 inhibitor with an IC50 value of 1.8 nM.

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Biological Activity

Tadalafil is a PDE5 inhibitor with an IC50 value of 1.8 nM.
PDE5 (Cell-free assay)
1.8 nM
In vitro (25°C) DMSO 70 mg/mL (179.76 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.68 mL 128.4 mL 256.81 mL
0.5 mM 5.14 mL 25.68 mL 51.36 mL
1 mM 2.57 mL 12.84 mL 25.68 mL
5 mM 0.51 mL 2.57 mL 5.14 mL

*The above data is based on the productmolecular weight 389.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10883
Actions Inhibitor
CAS No. 171596-29-5
Formula C22H19N3O4
M. Wt 389.4
Purity >98%
Synonyms Adcirca, Cialis

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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