Tadalafil
Catalog No.: A10883
PDE5 inhibitor
Tadalafil is a PDE5 inhibitor with an IC50 value of 1.8 nM.
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Adooq Products cited in reputable paper
Biological Activity
| Description | Tadalafil is a PDE5 inhibitor with an IC50 value of 1.8 nM. | ||
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Product Information
| Catalog Num | A10883 |
|---|---|
| Formula | C22H19N3O4 |
| Molecular Weight | 389.4 |
| CAS Number | 171596-29-5 |
| SMILES | CN1CC(=O)N2C(C1=O)CC3=C(C2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36 |
| Synonyms | Adcirca, Cialis |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 70 mg/mL (179.76 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.68 mL | 128.4 mL | 256.81 mL |
| 0.5 mM | 5.14 mL | 25.68 mL | 51.36 mL |
| 1 mM | 2.57 mL | 12.84 mL | 25.68 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
