Fig. 1 · Structure
Documents & Downloads
Tadnersen
Antisense Oligonucleotide
Tadnersen is an antisense oligonucleotide (ASO) designed to selectively target C9ORF72 transcript variants 1 and 3 with the hexanucleotide expansion. This targeted mechanism of action allows for modulation of gene expression associated with neurodegenerative diseases, particularly associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Tadnersen is utilized in research applications aimed at understanding the role of C9ORF72 in these conditions and evaluating potential therapeutic strategies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2170507-65-8 |
| Applications | Antisense Oligonucleotide |
| Synonyms | BIIB078; IONIS-C9Rx |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.