Fig. 1 · Structure
Documents & Downloads
TAK1-IN-2
TAK1 Inhibitor
TAK1-IN-2 is a potent and selective inhibitor of TAK1, exhibiting an IC50 of less than 2 nM. This compound effectively disrupts the TAK1 signaling pathway, playing a crucial role in the regulation of inflammatory responses and cell survival. TAK1-IN-2 is valuable for research in areas such as cancer biology, immunology, and the study of inflammatory diseases, facilitating investigations into the therapeutic potential of targeting TAK1.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2763213-98-3 |
| Applications | TAK1 Inhibitor |
| Formula | C26H26F2N6O5 |
| Molecular Weight | 540.52 |
| SMILES | O=C(C1=CC2=C(CN(C(C3=NC(C(N(CC4=CC=CC=C4OC(F)F)[C@H](C)C(NC)=O)=O)=CN3)=O)C2)C=C1)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.