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Talaglumetad hydrochloride

Catalog No.: A61780
mGluR2/3 agonist
Talaglumetad hydrochloride is a potent agonist of the type II metabotropic glutamate receptors, mGluR2 and mGluR3. It plays a crucial role in modulating synaptic transmission and is primarily utilized in research related to anxiety and neuropsychiatric disorders. Talaglumetad serves as a precursor to the more active compound, Eglumegad, facilitating studies aimed at understanding the therapeutic potential of mGluR2/3 modulation.
Talaglumetad hydrochloride 441765-97-5 mGluR2/3 agonist
Grouped product items
Size Price Stock Qty
1mg
$640.00
In stock
5mg
$1,810.00
In stock
10mg
$3,080.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTalaglumetad hydrochloride is a potent agonist of the type II metabotropic glutamate receptors, mGluR2 and mGluR3. It plays a crucial role in modulating synaptic transmission and is primarily utilized in research related to anxiety and neuropsychiatric disorders. Talaglumetad serves as a precursor to the more active compound, Eglumegad, facilitating studies aimed at understanding the therapeutic potential of mGluR2/3 modulation.
Product Information
Catalog NumA61780
FormulaC11H17ClN2O5
Molecular Weight292.72
CAS Number441765-97-5
SMILESO=C([C@@H](N)C)N[C@]([C@@]1([H])[C@]2([H])[C@@H]1C(O)=O)(CC2)C(O)=O.Cl
SynonymsLY-544344 hydrochloride
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Metabotropic glutamate receptors (mGluR)