Fig. 1 · Structure
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Talibegron hydrochloride
β3-Adrenoceptor Agonist
Talibegron hydrochloride is a potent β3-adrenoceptor agonist, demonstrating a pD2 value of 3.72 in phenylephrine-preconstricted rat mesenteric artery assays. This compound exhibits significant vasorelaxant activity, making it a valuable tool for research into cardiovascular and metabolic disorders. Its ability to modulate adrenergic pathways positions it as a potential candidate for studies focused on obesity, diabetes, and related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 178600-17-4 |
| Applications | β3-Adrenoceptor Agonist |
| Formula | C18H22ClNO4 |
| Molecular Weight | 351.82 |
| Synonyms | ZD2079 hydrochloride |
| SMILES | O=C(O)CC1=CC=C(OCCNC[C@H](O)C2=CC=CC=C2)C=C1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.