Fig. 1 · Structure
Documents & Downloads
Taltirelin acetate
TRH-R Superagonist
Taltirelin acetate is an acetate derivative of Taltirelin, functioning as a superagonist of the thyrotropin-releasing hormone receptor (TRH-R). This compound effectively increases cytosolic Ca2+ concentration with an EC50 of 36 nM, enhancing cell viability and reducing apoptosis in neurodegenerative models. Taltirelin exhibits neuroprotective effects in cellular and animal models of Parkinson's disease, and it also alleviates fatigue-like behaviors in mouse models associated with cancer-related fatigue, making it valuable for research in neurobiology and cancer therapeutics.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1549593-23-8 |
| Applications | TRH-R Superagonist |
| Formula | C19H27N7O7 |
| Molecular Weight | 465.46 |
| Synonyms | TA-0910 acetate |
| SMILES | O=C(N(CCC1)[C@@H]1C(N)=O)[C@@H](NC([C@@H](NC2=O)CC(N2C)=O)=O)CC3=CN=CN3.CC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.