TAM-IN-1 is a potent macrocyclic inhibitor targeting TAM receptors Axl and Mer, displaying binding affinities with Kis of 130 pM and <50 pM, respectively. This compound demonstrates significant biological activity in modulating pathways associated with tumor progression and immune evasion. TAM-IN-1 is applicable in research focused on cancer therapeutics and the study of receptor-mediated signaling in the tumor microenvironment.
TAM-IN-1 is a potent macrocyclic inhibitor targeting TAM receptors Axl and Mer, displaying binding affinities with Kis of 130 pM and <50 pM, respectively. This compound demonstrates significant biological activity in modulating pathways associated with tumor progression and immune evasion. TAM-IN-1 is applicable in research focused on cancer therapeutics and the study of receptor-mediated signaling in the tumor microenvironment.
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