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TAM558 intermediate-2

Catalog No.: A41156
Intermediate Product
TAM558 intermediate-2 is a critical intermediate in the synthesis of TAM558, a payload molecule used in the preparation of OMTX705. OMTX705 is a humanized antibody targeting fibroblast activation protein (FAP), which exhibits significant anti-tumor activity by binding to the cytolysin TAM470. This intermediate plays a vital role in facilitating the development of innovative therapeutic agents for cancer treatment.
TAM558 intermediate-2 2135877-76-6 Intermediate Product
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50mg
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTAM558 intermediate-2 is a critical intermediate in the synthesis of TAM558, a payload molecule used in the preparation of OMTX705. OMTX705 is a humanized antibody targeting fibroblast activation protein (FAP), which exhibits significant anti-tumor activity by binding to the cytolysin TAM470. This intermediate plays a vital role in facilitating the development of innovative therapeutic agents for cancer treatment.
Product Information
Catalog NumA41156
FormulaC29H50N4O5S
Molecular Weight566.80
CAS Number2135877-76-6
SMILESO=C(C1=CSC([C@H](OCCC)C[C@@H](N(CCC)C([C@@H](NC([C@@H]2N(C)CCCC2)=O)[C@@H](C)CC)=O)C(C)C)=N1)O
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Immunology & Inflammation > FAP