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TAM558

Catalog No.: A41408
OMTX705 Payload Molecule
TAM558 is a payload molecule utilized in the synthesis of OMTX705, a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470. This conjugation enhances the antitumor activity of OMTX705, making it a valuable tool in cancer research. The combination of TAM558 with targeted antibodies facilitates the development of innovative therapeutic strategies against tumor-associated fibroblasts.
TAM558 1802499-21-3 OMTX705 Payload Molecule
Grouped product items
Size Price Stock Qty
1mg
$470.00
In stock
5mg
$1,210.00
In stock
10mg
$1,980.00
In stock
25mg
$3,965.00
In stock
50mg
$6,195.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTAM558 is a payload molecule utilized in the synthesis of OMTX705, a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470. This conjugation enhances the antitumor activity of OMTX705, making it a valuable tool in cancer research. The combination of TAM558 with targeted antibodies facilitates the development of innovative therapeutic strategies against tumor-associated fibroblasts.
Product Information
Catalog NumA41408
FormulaC79H122N14O19S
Molecular Weight1603.96
CAS Number1802499-21-3
SMILESO=C([C@@H]1N(CCCC1)C)N[C@@H]([C@@H](C)CC)C(N(CCC)[C@@H](C(C)C)C[C@H](C2=NC(C(N[C@H](C[C@H](C)C(NNC(OCCOCCOCCOCCNC(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=C(C=C5)O)=O)=CS2)OCCC)=O
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Immunology & Inflammation > FAP