Tamoxifen-13C6 (ICI 47699-13C6) is a stable isotope-labeled variant of the selective estrogen receptor modulator (SERM), Tamoxifen (ICI 47699). This compound effectively blocks estrogen action in breast tissue while activating estrogenic pathways in other tissues such as bone, liver, and uterus. Additionally, it serves as a potent activator of the Hsp90 molecular chaperone, enhancing ATPase activity. Tamoxifen also demonstrates significant inhibitory effects against Ebola virus (EBOV Zaire) and Marburg virus (MARV) with IC50 values of 0.1 μM and 1.8 μM, respectively. Its biological activities include promoting autophagy, inducing apoptosis, and facilitating gene knockout in CreER transgenic mice, making it valuable for various research applications.
Tamoxifen-13C6 (ICI 47699-13C6) is a stable isotope-labeled variant of the selective estrogen receptor modulator (SERM), Tamoxifen (ICI 47699). This compound effectively blocks estrogen action in breast tissue while activating estrogenic pathways in other tissues such as bone, liver, and uterus. Additionally, it serves as a potent activator of the Hsp90 molecular chaperone, enhancing ATPase activity. Tamoxifen also demonstrates significant inhibitory effects against Ebola virus (EBOV Zaire) and Marburg virus (MARV) with IC50 values of 0.1 μM and 1.8 μM, respectively. Its biological activities include promoting autophagy, inducing apoptosis, and facilitating gene knockout in CreER transgenic mice, making it valuable for various research applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
