Fig. 1 · Structure

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Tankyrase-IN-3

TNKS1 Inhibitor

Tankyrase-IN-3 is a selective inhibitor of tankyrase 1 (TNKS1), demonstrating an IC50 value of 22 nM. This compound plays a significant role in the regulation of Wnt signaling pathways and cellular processes related to tumorigenesis. Tankyrase-IN-3 is primarily utilized in cancer research, offering insights into the therapeutic mechanisms targeting TNKS1 in various malignancies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 938893-79-9
Applications TNKS1 Inhibitor
Formula C21H21N5O4
Molecular Weight 407.42
SMILES
O=C(OCC(N1CCN(CC1)C2=CC=CC=N2)=O)CC(C3=CC=CC=C34)=NNC4=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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