Fig. 1 · Structure
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Tanshinlactone
Anti-tumor Agent
Tanshinlactone is a natural compound derived from Salvia miltiorrhiza, recognized for its anti-tumor properties. It induces methuocytic cell death (methuosis) through activation of the NRF2 pathway, demonstrating selective cytotoxicity towards ER+, HER2+/EGFR+ breast cancer cells. This compound is significant for research focused on breast cancer therapeutics and the study of coronavirus infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 105351-70-0 |
| Applications | Anti-tumor Agent |
| Formula | C17H12O3 |
| Molecular Weight | 264.28 |
| SMILES | O=C1C2=C3C=CC=C(C)C3=CC=C2C(OC=C4C)=C4O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.