Fig. 1 · Structure
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TAO Kinase inhibitor 1
TAOK Inhibitor
TAO Kinase inhibitor 1 is a selective ATP-competitive inhibitor of thousand-and-one amino acid kinases (TAOKs), exhibiting IC50 values of 11 nM for TAOK1 and 15 nM for TAOK2. This compound is known to effectively delay mitosis and induce mitotic cell death, making it a valuable research tool for studying cell cycle regulation and exploring potential therapeutic strategies in cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 850467-66-2 |
| Applications | TAOK Inhibitor |
| Formula | C25H24N2O2 |
| Molecular Weight | 384.47 |
| Synonyms | CP 43 |
| SMILES | O=C(CNC(C1=CC=C(C2=CC=CC=C2)C=C1)=O)NC(CCC3)C4=C3C=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.