Target & Activity
| Target | Activity | Value |
|---|---|---|
| EGFR |
Fig. 1 · Structure
Documents & Downloads
Tarlox-TKI
Tarlox-TKI is a compound with potential anti-cancer activity. It functions as a selective inhibitor of the P2Y receptor and exhibits binding affinity to the α7 nicotinic acetylcholine receptor, thereby preventing neuronal death and skin cancer progression. Tarlox-TKI has been demonstrated to inhibit xenograft tumor growth in murine models and to suppress the transcriptional regulation of genes associated with autoimmune diseases. In addition, Tarlox-TKI interacts with toll-like receptor 4 (TLR4) and inhibits the expression of 2-aminoethoxydiphenyl borate (APBD). It also prevents the activation of p21 through inhibition of polymerase chain reaction (PCR), resulting in the suppression of leukemia inhibitory factor (LIF).
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2135696-72-7 |
| Formula | C19H18BrClN6O |
| Molecular Weight | 461.74 |
| SMILES | BrC1=C(Cl)C=CC(NC2=NC=NC3=CN=C(NC(/C=C/CN(C)C)=O)C=C32)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.