Fig. 1 · Structure

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TASP0315003

GlyT1 Inhibitor

TASP0315003 is a selective inhibitor of the glycine transporter 1 (GlyT1). By inhibiting GlyT1, TASP0315003 enhances NMDA receptor function through elevated synaptic glycine levels. This compound demonstrates potential in addressing cognitive dysfunction and negative symptoms associated with schizophrenia while minimizing adverse central nervous system effects. TASP0315003 is suitable for research applications in neurological diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1007109-16-1
Applications GlyT1 Inhibitor
Formula C24H25ClF3N5O
Molecular Weight 491.94
SMILES
O=C(C1=NC=CC(C(F)(F)F)=C1Cl)NC(C2=CC=CC(C3=CN(CC)N=C3)=C2)[C@H]4NCCCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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