Fig. 1 · Structure
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Tauro-obeticholic acid sodium
Obeticholic acid Metabolite
Tauro-obeticholic acid sodium is the active metabolite of Obeticholic acid and functions as a selective and potent agonist of the farnesoid X receptor (FXR). This compound is primarily utilized in the study of metabolic diseases, liver function, and bile acid metabolism. Its relevance in research includes exploring therapeutic avenues for conditions such as non-alcoholic fatty liver disease (NAFLD) and cholestasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2278141-79-8 |
| Applications | Obeticholic acid Metabolite |
| Formula | C28H48NNaO6S |
| Molecular Weight | 549.74 |
| SMILES | C[C@H](CCC(NCCS(=O)(O[Na])=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.