Fig. 1 · Structure
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Taurohyocholic acid
Taurine-Conjugated Hyocholic Acid
Taurohyocholic acid is a taurine-conjugated hyocholic acid that serves as a predictive biomarker for the effectiveness of tyrosine kinase inhibitors in conjunction with PD-1 inhibitors in the treatment of hepatocellular carcinoma (HCC). This compound is essential for investigations into the therapeutic outcomes of combination therapies in cancer research, particularly in understanding the mechanisms underlying drug response and resistance in HCC.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 32747-07-2 |
| Applications | Taurine-Conjugated Hyocholic Acid |
| Formula | C26H45NO7S |
| Molecular Weight | 515.70 |
| Synonyms | THCA |
| SMILES | O[C@@H]1CC[C@]2([C@@]([H])(C1)[C@H]([C@H]([C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@@]4([C@@H](CCC(NCCS(O)(=O)=O)=O)C)[H])[H])C)[H])[H])O)O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.