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Tauromustine

Anticancer Agent

Tauromustine is an orally active nitrosourea with significant anticancer properties, primarily functioning through DNA alkylation and damage. It demonstrates potent efficacy in various cancer models, including Walker 256 rat sarcoma, melanoma, breast cancer, pleural mesothelioma, and ovarian cancer. With a favorable therapeutic index, tauromustine is metabolized in the liver, producing cytotoxic metabolites that contribute to its overall activity. This compound is valuable for research applications aimed at understanding cancer mechanisms and developing effective therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	85977-49-7
Applications	Anticancer Agent
Formula	C₇H₁₅ClN₄O₄S
Molecular Weight	286.74
SMILES	O=NN(CCCl)C(NCCS(=O)(N(C)C)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.