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Tazolol

β-adrenergic Antagonist

Tazolol is a selective β-adrenergic antagonist, exhibiting an IC50 of 700 nM in inhibiting the accumulation of cyclic AMP in rat cortical slices when stimulated by (-) isoproterenol. This compound significantly enhances cardiac output and stroke volume, making it a valuable tool in the study of heart failure. Tazolol's capacity to modulate β-adrenergic signaling offers insights into cardiovascular physiology and potential therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	39832-48-9
Applications	β-adrenergic Antagonist
Formula	C₉H₁₆N₂O₂S
Molecular Weight	216.30
SMILES	OC(CNC(C)C)COC1=NC=CS1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.