Fig. 1 · Structure

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TB-11

Cat. No. A39890 CAS 1415033-93-0

Cathepsin D Inhibitor

TB-11 is a potent Cathepsin D inhibitor, demonstrating an IC50 of 0.126 nM for Cathepsin D, alongside inhibitory activity of 1.92 nM for Cathepsin E and 48.8 nM for BACE1. This compound is valuable for research focused on tumor biology and the role of cathepsins in cancer progression. Its selectivity and potency make it a useful tool for investigating the therapeutic potential of Cathepsin D inhibition in various oncological studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1415033-93-0
Applications Cathepsin D Inhibitor
Formula C52H78N8O12
Molecular Weight 1007.22
SMILES
CC(C)(C)OC(N[C@@H](C(C)C)C(N(C)[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)[C@@H](O)CC(N[C@@H](CC(C)C)C(N[C@@H](C)C(N(C)[C@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(OC)=O)=O)=O)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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