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TBK1 ligand 2-C-O-C4-O-C3-O-C-amide

Target Protein Ligand-Linker Conjugate

TBK1 ligand 2-C-O-C4-O-C3-O-C-amide is a protein ligand-linker conjugate specifically designed to facilitate the development of targeted protein degraders. This compound serves as a crucial component in the synthesis of the PROTAC TBK1 degrader-2, enabling selective degradation of the TBK1 protein. Its application in chemical biology research allows for the investigation of TBK1's role in various cellular processes and the potential modulation of its activity.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2052306-12-2
Applications	Target Protein Ligand-Linker Conjugate
Formula	C₃₁H₄₆BrN₅O₇
Molecular Weight	680.63
SMILES	O=C(COCCCOCCCCOCCCOC1=CC=C(NC2=NC=C(C(NCCCN(C)C(C3CCC3)=O)=N2)Br)C=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.