Fig. 1 · Structure
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TbPTR1 inhibitor 2
PTR1 Inhibitor
TbPTR1 inhibitor 2 is a potent inhibitor of the PTR1 enzyme, demonstrating IC50 values of 34.2 μM for TbPTR1 and 32.9 μM for LmPTR1. This compound exhibits significant anti-parasitic activity against Trypanosoma brucei, making it a valuable tool for research in the field of parasitology. Its selective inhibition profile supports studies aimed at exploring PTR1's role in pathogen metabolism and resistance mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 17557-67-4 |
| Applications | PTR1 Inhibitor |
| Formula | C8H8N2O2S2 |
| Molecular Weight | 228.29 |
| SMILES | NC1=NC2=CC=C(S(=O)(C)=O)C=C2S1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.