Fig. 1 · Structure

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TBS-rG(Ac)

Nucleoside

TBS-rG(Ac) is a modified guanosine ribonucleotide featuring a TBS protecting group that prevents hydroxyl group reactivity and an acetyl substitution. This compound serves as an essential building block in nucleic acid synthesis and is useful for studying RNA stability and function. Its unique modifications facilitate further applications in oligonucleotide chemistry and bioconjugation research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1256468-15-1
Applications Nucleoside
Formula C39H47N5O8Si
Molecular Weight 741.90
SMILES
O=C1C2=C(N([C@H]3[C@H](O[Si](C)(C(C)(C)C)C)[C@H](O)[C@@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)O3)C=N2)NC(NC(C)=O)=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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