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TC-6683

α4β2 nAChR Agonist

TC-6683 is a selective agonist of the α4β2 nicotinic acetylcholine receptor (nAChR). This compound has shown potential in modulating cholinergic signaling pathways and is primarily utilized in research related to neurological disorders, particularly cognitive dysfunction. Although TC-6683 demonstrated limited therapeutic efficacy in an animal model of DYT1 dystonia, its role in studying nAChR dynamics makes it a valuable tool for investigating various neurobiological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	1025007-04-8
Applications	α4β2 nAChR Agonist
Formula	C₁₁H₁₃ClN₂O₂
Molecular Weight	240.69
Synonyms	AZD1446
SMILES	O=C(N1CC2CNCC2C1)C3=CC=C(Cl)O3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.