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TNKS inhibitor
In Stock
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| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| HEK293 | IC50 | 0.215 μM | Inhibition of mouse Wnt3A signaling in human HEK293 cells after 1 day by super top flash luciferase reporter gene assay | [PMID: 22260203] |
| SW480 | EC50 | 0.709 μM | Stabilization of Axin2 in human SW480 cells after 24 hrs by sandwich ELISA | [PMID: 22260203] |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 865565-29-3 |
| Applications | TNKS inhibitor |
| Formula | C20H19N5O3S |
| Molecular Weight | 409.46 |
| SMILES | CC(N1C(C=C2)=CC=C2OC)=NN=C1SCC3=NC(C(C=C4)=CC=C4OC)=NO3 |
No reported solubility data are available for this product.
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
