Fig. 1 · Structure
Documents & Downloads
TC-I 15
α2β1 Inhibitor
TC-I 15 is an allosteric inhibitor targeting the integrin α2β1, with additional inhibition of α1β1 and α11β1. This compound effectively inhibits platelet adhesion to collagen and thrombus formation. Additionally, TC-I 15 disrupts the formation of a pre-metastatic microenvironment by preventing the uptake of cancer-associated fibroblast extracellular vesicles by lung fibroblasts, thus reducing the metastatic potential of salivary gland adenocystic carcinoma in mouse models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 916734-43-5 |
| Applications | α2β1 Inhibitor |
| Formula | C23H28N4O6S2 |
| Molecular Weight | 520.62 |
| SMILES | O=[S](N(CSC(C)1C)[C@@H]1C(N[C@H](C(O)=O)CNC(NCC2=CC=CC=C2)=O)=O)(C3=CC=CC=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.