Fig. 1 · Structure
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TC-Mps1-12
Cat. No.
A55061
CAS
1206170-62-8
Mps1 Inhibitor
TC-Mps1-12 is a highly selective inhibitor of monopolar spindle 1 (Mps1), demonstrating an IC50 of 6.4 nM. It effectively disrupts the function of Mps1, a key regulator of the mitotic spindle assembly checkpoint. This compound is valuable for studying cell cycle regulation, mitosis, and cancer biology, facilitating research into potential therapeutic targets for cancer treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1206170-62-8 |
| Applications | Mps1 Inhibitor |
| Formula | C17H20N6O |
| Molecular Weight | 324.38 |
| SMILES | N#CC1=C(N=C(NC2=CC=C(C(N)=O)C=C2)C=C1N)NC(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.