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TCCNeu5Ac

Catalog No.: B20820
Trisaccharide Glycan Ligand
TCCNeu5Ac is a high-affinity trisaccharide glycan ligand that specifically targets Siglec-1 (CD169). This compound features an azide group that allows for versatile conjugation to lipids, enabling selective targeting of CD169-expressing cells in vitro and facilitating in vivo delivery to CD169-positive macrophages. TCCNeu5Ac serves as an effective tool for research in macrophage biology and cellular targeting applications.
TCCNeu5Ac 3036471-42-5 Trisaccharide Glycan Ligand
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTCCNeu5Ac is a high-affinity trisaccharide glycan ligand that specifically targets Siglec-1 (CD169). This compound features an azide group that allows for versatile conjugation to lipids, enabling selective targeting of CD169-expressing cells in vitro and facilitating in vivo delivery to CD169-positive macrophages. TCCNeu5Ac serves as an effective tool for research in macrophage biology and cellular targeting applications.
Product Information
Catalog NumB20820
FormulaC39H51N6NaO20S
Molecular Weight978.91
CAS Number3036471-42-5
SMILESOC([C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CNC(C2=CC(COC3=CC=CC=C34)=C4S2)=O)O[C@@H]5[C@H]([C@@H](O[C@@H]([C@@H]5O)CO)O[C@@H]6[C@H](O[C@H]([C@@H]([C@H]6O)NC(C)=O)OCCN=[N+]=[N-])CO[Na])O)=O
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