Fig. 1 · Structure
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TCEP-d12 hydrochloride
Stable Isotope
TCEP-d12 hydrochloride is a deuterated form of Tris(2-carboxyethyl)phosphine hydrochloride, functioning as a non-thiol reducing agent with enhanced stability and faster disulfide bond reduction compared to conventional reductants. Its selective ability to reduce protein disulfides without interfering with thiol-directed reactions makes it valuable in various biochemical applications. TCEP-d12 hydrochloride is widely utilized in DNA and gold nanoparticle (AuNP) chemistry, facilitating efficient reactions while preserving the integrity of the target molecules.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1189959-10-1 |
| Applications | Stable Isotope |
| Formula | C9H4D12ClO6P |
| Molecular Weight | 298.72 |
| Synonyms | Tris(2-carboxyethyl)phosphine hydrochloride-d12 |
| SMILES | OC(C([2H])([2H])C([2H])([2H])P(C([2H])([2H])C([2H])([2H])C(O)=O)C([2H])([2H])C([2H])([2H])C(O)=O)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.