TCMCB07

Catalog No.: A61627
MC4R Antagonist
TCMCB07 is a cyclic nonapeptide that functions as an antagonist of the melanocortin receptor 4 (MC4R). This compound demonstrates significant potential in the study of cachexia, exhibiting oral bioavailability and the ability to penetrate the blood-brain barrier. Its unique structure may also confer additional transport capabilities, making it a valuable tool in related research applications.
Grouped product items
Size Price Stock Qty
5mg
$125.00
In stock
10mg
$200.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTCMCB07 is a cyclic nonapeptide that functions as an antagonist of the melanocortin receptor 4 (MC4R). This compound demonstrates significant potential in the study of cachexia, exhibiting oral bioavailability and the ability to penetrate the blood-brain barrier. Its unique structure may also confer additional transport capabilities, making it a valuable tool in related research applications.
Product Information
Catalog NumA61627
FormulaC63H87N15O11
Molecular Weight1230.46
CAS Number1456699-27-6
SequenceAc-Nle-c[Asp-Pro-D-Nal(2')-Arg-Trp-Lys]-dVal-dPro-NH2
SMILESC(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC5=C(C=C4)C=CC=C5)NC(=O)[C@]6(N(C(=O)[C@@H](NC([C@H](CCCC)NC(C)=O)=O)CC(=O)NCCCC[C@@H](C(N[C@@H](C(=O)N7[C@@H](C(N)=O)CCC7)[C@H](C)C)=O)NC3=O)CCC6)[H]
SynonymsMifomelatide
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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