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TCR-IN-2

TCR Inhibitor

TCR-IN-2 is a T cell receptor (TCR) inhibitor that selectively targets TCR-mediated signaling. It effectively inhibits the phosphorylation of CD3ζ, resulting in the suppression of cytokine release, specifically IFNγ and IL-2. This compound is valuable for research focused on understanding T cell activation mechanisms and exploring therapeutic strategies for modulating immune responses in various disease contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2375043-73-3
Applications	TCR Inhibitor
Formula	C₂₄H₂₄F₃NO₄
Molecular Weight	447.45
SMILES	OC(CCOC1=CC=C(OCC(CN2CCCC2)=C3C4=CC=C(C(F)(F)F)C=C4)C3=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.