tcY-NH2 TFA

Catalog No.: A63469
PAR4 Antagonist
tcY-NH2 TFA is a potent selective antagonist of the protease-activated receptor 4 (PAR4). This peptide effectively inhibits thrombin- and AY-NH2-induced platelet aggregation as well as endostatin release. tcY-NH2 TFA is valuable for research in the fields of inflammation and immunology, providing insights into platelet function and related signaling pathways.
Grouped product items
Size Price Stock Qty
1mg
$70.00
In stock
5mg
$215.00
In stock
10mg
$355.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptiontcY-NH2 TFA is a potent selective antagonist of the protease-activated receptor 4 (PAR4). This peptide effectively inhibits thrombin- and AY-NH2-induced platelet aggregation as well as endostatin release. tcY-NH2 TFA is valuable for research in the fields of inflammation and immunology, providing insights into platelet function and related signaling pathways.
Product Information
Catalog NumA63469
FormulaC42H50F3N7O9
Molecular Weight853.88
CAS Number1262750-73-1
Sequence shortening{trans-Cinnamoyl}-YPGKF-NH2
SMILESC(C(O)=O)(F)(F)F.C([C@H](CC1=CC=C(O)C=C1)NC(/C=C/C2=CC=CC=C2)=O)(=O)N3[C@H](C(NCC(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)CCCCN)=O)=O)CCC3
Synonyms(trans-Cinnamoyl)-YPGKF-NH2 TFA
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