Fig. 1 · Structure

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TEAD ligand 1

Ligand for Target Protein for PROTAC

TEAD Ligand 1 is a specific ligand for the transcriptional enhancer factor TEAD. It serves as a crucial building block for the synthesis of PROTAC TEAD degrader-1, facilitating targeted degradation of TEAD proteins. This compound is essential for studies involving protein-protein interactions and the modulation of TEAD-related pathways in various biological research applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2971850-47-0
Applications Ligand for Target Protein for PROTAC
Formula C25H18BrF3N2O
Molecular Weight 499.32
SMILES
O=C(C1=CC=C2C(C3=CC=C(C(F)(F)F)C=C3)=CC=CC2=C1)N[C@H](C4=NC(Br)=CC=C4)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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