Tebuconazole-d9 is a deuterium-labeled derivative of the azole fungicide Tebuconazole, primarily targeting cytochrome P450 51 (CYP51). It exhibits potent inhibitory activity with IC50 values of 0.9 μM against Candida albicans CYP51 and 1.3 μM against truncated human CYP51 (Δ60HsCYP51). This stable isotope is valuable for studies involving fungicidal mechanisms and metabolic pathways in both agricultural and biomedical research.
Tebuconazole-d9 is a deuterium-labeled derivative of the azole fungicide Tebuconazole, primarily targeting cytochrome P450 51 (CYP51). It exhibits potent inhibitory activity with IC50 values of 0.9 μM against Candida albicans CYP51 and 1.3 μM against truncated human CYP51 (Δ60HsCYP51). This stable isotope is valuable for studies involving fungicidal mechanisms and metabolic pathways in both agricultural and biomedical research.
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