Fig. 1 · Structure
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Tecalcet
CaSR Modulator
Tecalcet is an orally active calcimimetic compound that allosterically modulates the calcium-sensing receptor (CaSR), enhancing its sensitivity to extracellular calcium ions (Ca2+). This modulation leads to increased intracellular signaling pathways relevant to calcium homeostasis. Tecalcet is primarily used in research focusing on calcium metabolism, parathyroid hormone regulation, and related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 148717-54-8 |
| Applications | CaSR Modulator |
| Formula | C18H22ClNO |
| Molecular Weight | 303.83 |
| Synonyms | R-568; NPS R-568 free base |
| SMILES | ClC1=CC=CC=C1CCCN[C@H](C)C2=CC=CC(OC)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.