Fig. 1 · Structure
Documents & Downloads
Tecovirimat
Antipoxvirus Compound
Tecovirimat is a selective antiviral compound that targets orthopoxviruses, such as vaccinia, monkeypox, camelpox, cowpox, ectromelia, and variola viruses. Its mechanism involves inhibiting the orthopoxvirus protein VP37, which is essential for the membrane envelopment of intracellular mature virus particles, thereby preventing the formation of enveloped viruses. Tecovirimat demonstrates potent antiviral activity, with EC50 values of 0.01 μM against vaccinia virus, 0.48 μM against cowpox virus, and 0.05 μM against ectromelia virus. This compound serves as a valuable tool for research into poxvirus pathogenesis and therapeutic interventions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 869572-92-9 |
| Applications | Antipoxvirus Compound |
| Formula | C19H15F3N2O3 |
| Molecular Weight | 376.33 |
| Synonyms | ST-246 |
| SMILES | O=C(NN(C([C@]1([H])[C@@]2([H])[C@@](C3)([H])[C@@]3([H])[C@@](C=C2)([H])[C@]41[H])=O)C4=O)C5=CC=C(C(F)(F)F)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.