Fig. 1 · Structure
Documents & Downloads
Telotristat besilate
Tryptophan Hydroxylase Inhibitor
Telotristat besilate is a potent inhibitor of tryptophan hydroxylase, exhibiting an in vivo IC50 of 0.028 μM. This compound effectively modulates serotonin synthesis, making it a valuable tool for research on serotonin-related disorders and other neurochemical pathways. Its application extends to studies investigating the regulation of mood, gastrointestinal function, and tumor activity in carcinoid syndrome.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1374745-52-4 |
| Applications | Tryptophan Hydroxylase Inhibitor |
| Formula | C31H28ClF3N6O6S |
| Molecular Weight | 705.10 |
| SMILES | N[C@H](C(O)=O)CC1=CC=C(C=C1)C2=NC(N)=NC(O[C@@H](C(F)(F)F)C3=CC=C(C=C3N4N=C(C=C4)C)Cl)=C2.O=S(C5=CC=CC=C5)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.