Fig. 1 · Structure
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Temocaprilat
ACE Inhibitor
Temocaprilat is a potent inhibitor of angiotensin-converting enzyme (ACE), which plays a crucial role in the regulation of blood pressure and fluid balance. This compound has been shown to mitigate the inhibitory effects of high glucose levels on the proliferation of aortic endothelial cells, suggesting potential benefits in cardiovascular health. Temocaprilat is primarily utilized in research related to hypertension and vascular inflammation, providing valuable insights into these critical areas of study.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 110221-53-9 |
| Applications | ACE Inhibitor |
| Formula | C21H24N2O5S2 |
| Molecular Weight | 448.56 |
| Synonyms | Temocapril diacid; Temocaprilate; RS 5139 |
| SMILES | OC(CN1C[C@@H](C2=CC=CS2)SC[C@@H](C1=O)N[C@H](C(O)=O)CCC3=CC=CC=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.