Fig. 1 · Structure
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Temozolomide acid
Anticancer Agent
Temozolomide acid is a carboxylic acid derivative of Temozolomide, functioning primarily as an anticancer agent. It acts as a DNA alkylating agent, specifically methylating the guanine and adenine bases of DNA, which leads to DNA double-strand breaks, cell cycle arrest, and subsequent cell death. This compound is particularly valuable for research applications focused on glioblastoma and other forms of brain cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 113942-30-6 |
| Applications | Anticancer Agent |
| Formula | C6H5N5O3 |
| Molecular Weight | 195.14 |
| SMILES | CN1N=NC2=C(N=CN2C1=O)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.