Fig. 1 · Structure
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Tempo
Nitroxide Radical
Tempo is a nitroxide radical that functions as a selective scavenger of reactive oxygen species (ROS) in mitochondria. It serves as an organocatalyst, effectively disproportionating superoxide and oxidizing primary alcohols to aldehydes within a catalytic cycle. Notably, Tempo exhibits both mutagenic and antioxidant activities, capable of inducing DNA strand breaks. Additionally, it demonstrates cytotoxic and mutagenic effects in mouse lymphoma cells, making it a valuable reagent for research on oxidative stress and cellular damage.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2564-83-2 |
| Applications | Nitroxide Radical |
| Formula | C9H18NO |
| Molecular Weight | 156.25 |
| SMILES | [O]N1C(C)(C)CCCC1(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.