Home /
Apoptosis /
p53 /
Tenovin-1

Tenovin-1

Name: Tenovin-1
Brand: Adooq Bioscience
SKU: A11943
Rating: 100 (268 reviews)

Catalog No.: A11943

p53 activator

Tenovin-1 Chemical Structure

CAS NO. 380315-80-0

Tenovin-1 is a small molecule activator of p53 transcriptional activity that protects against MDM2-mediated p53 degradation.

Availability: In stock

Package	Price	Qty
25 mg	$80.00
50 mg	$140.00
100 mg	$250.00
10mM * 1mL in DMSO	$71.00
Custom Size	Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Bulk Inquiry

Price Match

Add to Wishlist

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable papers

Biological Activity

Tenovin-1 is a small molecule activator of p53 transcriptional activity that protects against MDM2-mediated p53 degradation.

Targets

p53	Mdm2

Solubility *

In vitro (25°C)	DMSO	65 mg/mL (175.92 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	15% Captisol	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.06 mL	135.32 mL	270.64 mL
0.5 mM	5.41 mL	27.06 mL	54.13 mL
1 mM	2.71 mL	13.53 mL	27.06 mL
5 mM	0.54 mL	2.71 mL	5.41 mL

*The above data is based on the productmolecular weight 369.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11943
Actions	Activator
CAS No.	380315-80-0
Formula	C20H23N3O2S
M. Wt	369.5
Solubility	DMSO
Purity	>98%
SMILES	CC(=O)NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.