Tenovin-1

Catalog No.: A11943

p53 activator

Tenovin-1

Tenovin-1 Chemical Structure

CAS NO. 380315-80-0

Tenovin-1 is a small molecule activator of p53 transcriptional activity that protects against MDM2-mediated p53 degradation.

Availability: In stock

Package Price Qty
25 mg

Regular Price: $80.00

Special Price $64.00

50 mg

Regular Price: $140.00

Special Price $112.00

100 mg

Regular Price: $250.00

Special Price $200.00

10mM * 1mL in DMSO
$71.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Tenovin-1 is a small molecule activator of p53 transcriptional activity that protects against MDM2-mediated p53 degradation.
Targets
p53 Mdm2
In vitro (25°C) DMSO 74 mg/mL (200.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.06 mL 135.32 mL 270.64 mL
0.5 mM 5.41 mL 27.06 mL 54.13 mL
1 mM 2.71 mL 13.53 mL 27.06 mL
5 mM 0.54 mL 2.71 mL 5.41 mL

*The above data is based on the productmolecular weight 369.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A11943
Actions Activator
M. Wt 369.5
Formula C20H23N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 380315-80-0
Synonyms N/A
SMILES CC(=O)NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C

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