TEPP-46

Catalog No.: A16279
PKM2 activator
TEPP-46 is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2) with half-maximum activating concentration (AC50 value) of 92 nM, and little or no activity versus PKM1, PKL and PKR.
Grouped product items
Size Price Stock Qty
1mg
$35.00
In stock
5mg
$75.00
In stock
10mg
$135.00
In stock
25mg
$240.00
In stock
50mg
$365.00
In stock
100mg
$550.00
In stock
500mg
$1,215.00
In stock
10mM * 1mL in DMSO
$90.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Adooq Products cited in reputable paper
Biological Activity
Discription TEPP-46 is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2) with half-maximum activating concentration (AC50 value) of 92 nM, and little or no activity versus PKM1, PKL and PKR.
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A16279
Formula C17H16N4O2S2
Molecular Weight 372.46
CAS Number 1221186-53-3
SMILES O=C1C(N(C)C2=C3SC(S(C)=O)=C2)=C3C=NN1CC4=CC=CC(N)=C4
Synonyms ML-265
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 73 mg/mL (195.99 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.85 mL 134.24 mL 268.49 mL
0.5 mM 5.37 mL 26.85 mL 53.7 mL
1 mM 2.68 mL 13.42 mL 26.85 mL
5 mM 0.54 mL 2.68 mL 5.37 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy TEPP-46 | TEPP-46 Supplier | purchase TEPP-46 | TEPP-46 cost | TEPP-46 manufacturer | order TEPP-46 | TEPP-46 distributor | buy 1221186-53-3 | 1221186-53-3 Supplier | purchase 1221186-53-3 | 1221186-53-3 cost | 1221186-53-3 manufacturer | order 1221186-53-3 | 1221186-53-3 distributor