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Terrestrosin D

Catalog No.: A30298
HSP90AA1 Interactor, CNR1 Interactor, DRD2 Interactor,
Terrestrosin D is a small molecule that interacts with HSP90AA1, CNR1, and DRD2, functioning as an orally active apoptosis inducer. It effectively induces cell cycle arrest at the G1 and S phases while diminishing mitochondrial membrane potential, leading to the inhibition of growth in both cancer and endothelial cells. This compound is under investigation for its potential therapeutic applications in castration-resistant prostate cancer and pulmonary fibrosis.
Terrestrosin D 179464-23-4 HSP90AA1 Interactor, CNR1 Interactor, DRD2 Interactor,
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Size Price Stock Qty
1mg
$30.00
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5mg
$75.00
In stock
10mg
$115.00
In stock
25mg
$190.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTerrestrosin D is a small molecule that interacts with HSP90AA1, CNR1, and DRD2, functioning as an orally active apoptosis inducer. It effectively induces cell cycle arrest at the G1 and S phases while diminishing mitochondrial membrane potential, leading to the inhibition of growth in both cancer and endothelial cells. This compound is under investigation for its potential therapeutic applications in castration-resistant prostate cancer and pulmonary fibrosis.
Product Information
Catalog NumA30298
FormulaC50H80O23
Molecular Weight1049.16
CAS Number179464-23-4
SMILESC[C@@]12[C@]3([H])[C@](O[C@]4(CC[C@@H](C)CO4)[C@H]3C)([H])C[C@@]1([H])[C@@]5([H])[C@]([C@@]6([C@@](C[C@@H](O[C@]7([H])O[C@@H]([C@H](O[C@@]8([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O8)O[C@@]9([H])[C@@H]([C@H]([C@H](O)CO9)O)O)O[C@]%10([H])O[C@@H]([C@H](O)[C@H](O)[C@H]%10O)CO)[C@H](O)[C@H]7O)CO)CC6)([H])CC5)C)([H])CC2=O
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Metabolism > HSP