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Biological Activity
Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.48 mL | 122.41 mL | 244.82 mL |
| 0.5 mM | 4.9 mL | 24.48 mL | 48.96 mL |
| 1 mM | 2.45 mL | 12.24 mL | 24.48 mL |
| 5 mM | 0.49 mL | 2.45 mL | 4.9 mL |
*The above data is based on the productmolecular weight 408.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A20891 |
|---|---|
| Actions | Agonist |
| CAS No. | 251565-85-2 |
| Formula | C20H24O7S |
| M. Wt | 408.47 |
| Purity | >98% |
| SMILES | O=C(O)[[email protected]@H](OCC)CC1=CC=C(OCCC2=CC=C(OS(=O)(C)=O)C=C2)C=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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